One of the most common causes for thinning hair and receding hairlines is thought to be high levels of stress.
Stress leads to a variety of negative consequences in the body, which can individually lead to hair loss and combine to lead to cases of male-pattern baldness and alopecia.
One particular cause of lost hair has been linked to corticotropin releasing factor, the levels of which increase when people are under stress. Astressin B also reduces cortisol levels, which is another chemical agent of stress and has been linked to balding.
It is possible, through the artificial introduction of increased levels of Astressin B, to reduce the negative impact of stress on the body and decrease the potential for hair loss associated with stress.
There is potential for Astressin B treatments to be used in coordination with other methods of addressing hair loss, which will help prevent the negative impact of stress on hair growth.
What is Astressin B?
Astressin B is a corticotropin releasing hormone antagonist and is a naturally occurring chemical. Astressin B is a chemically heavy peptide that is unable to pass through the skin and cell barriers, and is therefore only able to be utilized through injection.
There is significant research available on the ability of Astressin B to reduce levels of corticotropin releasing factor, which is a product of stress and related to numerous issues including a negative impact on digestion. In a study published by Wiley Online, the authors discuss positive impact of gastric motility in rodents.
How Astressin B Effects Hair Loss
One of the commonly identified underlying causes for thinning hair can be high levels of stress and chronic stress. This occurs due to numerous negative impacts of stress on the body, including the production of corticotropin releasing factor.
Due to the ability of Astressin B to reduce the presence of chemical agents related to stress, it is possible that Astressin B may be an effective method of reducing issues of hair loss related to stress.
In research published by the US National Library of Medicine, the authors found that the use of Astressin B injections revived hair follicle growth in comparison to saline injections (the control) in rodent populations (See Fig. 1).
It was hypothesized that the capacity for Astressin B to inhibit the corticotropin releasing factor which occurs during the stress response of an organism. There is significant research to suggest that high levels of corticotropin releasing factor present in the body can lead to the inhibition of hair growth.
Row A: Male mice (4 months old) injected once daily for 5 consecutive days with saline at 3 days after the last injection.
Row B: astressin-B (5 µg/mouse) at 3 days after the last ip injection.
Row C: the same mice as in the middle panel Row B at 4 weeks after the last ip injection.
It’s clear to see by comparing row A and B that the astressin-b solution has helped the hair follicles recover more than the saline solution.
According to the journal Advances in Experimental Medicine and Biology, the use of Astressin B has been shown to reverse hair thinning and promote healthy hair growth.
The combination of a taurine and Astressin B treatment was shown to reduce levels of chemical compounds that are created in stress reactions. This study is merely corollary, with the potential for this treatment to reduce the chemicals that are responsible for balding.
Research found that such a treatment would be complementary to the use of commercially available treatments for hair loss.
Some leading professionals believe that Astressin B may be able to increase the likelihood that the implantation of hair follicle clones is more likely to be successful when utilizing Astressin B treatments.
Typically, the implantation of hair follicle clones will be successful for short term periods of time and then will begin to fall out.
Based on the limited available research, the use of Astressin B in combination with other available treatments to address thinning hair with a specific origin.
Much of the experimentation has been done on animals and does not include human clinical trials, therefore more research is needed to confirm the efficacy of Astressin B as a hair loss treatment as well as the safety.
Potential Side Effects of Astressin B
The mechanism of action of Astressin B will lower the levels of cortisol within the body, which can lead to numerous negative symptoms and side effects.
While high levels of cortisol will also have negative effects on the body, problems can arise when artificially lowering cortisol levels through the use of a product such as Astressin B.
Anyone considering the use of Astressin B to treat hair fall should consult with a medical professional to ensure it will be safe.
The following are potential symptoms and side effects of low cortisol levels induced by Astressin B use:
- depression or anxiety
- dizziness or feeling faint
- fatigue and weakness
- heart palpitations
- emotional hypersensitivity
- inability to cope with stress
- muscle weakness
- lower back pain
- -skin sensitivity
- nausea, vomiting, diarrhea
- abdominal pain
- jittery feelings
- confusion and clumsiness
- motion sickness
- difficulty sleeping or insomnia
- frequent urination
- irregularities in menstrual cycles
There is very limited research on the impact of utilizing Astressin B injections to treat cases of thinning hair and balding. Based on the existing research, the use of Astressin B may be a reasonable complementary treatment in concert with other forms of hair loss treatments.
Currently, the only available treatments are through injection and oral medications are still in the development phase.
Any topical solutions claiming to be comprised of Astressin B are very unlikely to have any significant impact on hair growth, however there is the potential for Astressin B treatments to impact hair loss that is being caused by chronic or high levels of stress.
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