MSM clinical studies of hair growth positive results

MSM for Hair Growth: Does It Really Work?

There are a variety of products on the market, including Rogaine and Propecia, that aim to target hair loss.

What if I told you, however, that a supplement which is found naturally in our bodies and abundantly throughout the world, might help to lessen hair loss and even promote hair growth?

In this post I’m going to introduce you to MSM, a sulfur-rich compound which has been slowly gaining some buzz over the years.

You’ll learn what MSM is, and how it’s believed to work to promote hair growth. I’ll also highlight the scientific research showing MSM’s effectiveness at promoting hair growth in mice.

What is MSM?

MSM is a sulfur-rich compound

MSM stands for methylsulfonylmethane (1).This sulfur-rich, organic compound is used in a variety of industries, including health and beauty, pharmaceutical, and food (2).

Known by a few other names, including DMSO2, methyl sulfone, and dimethyl sulfone, MSM is found abundantly in nature, as sulfur is one of the building blocks of life.

How Does MSM Work?

To understand how MSM works to promote hair growth, let’s first take a look at the structure of hair.

The shaft of the hair is made up of a three-layered structure (3). On the inside is the medulla. Surrounding the medulla is the cortex, the most fibrous part of the hair strand which contains mostly keratin and structural lipids. On the outside of the hair is the cuticle, consisting of dead skin cells which form a protective layer around the hair.

Focusing in on the cortex and its keratin-based structure, we find a sulfur-rich environment (4).

Now, as mentioned above, sulfur is a building block of life. It’s the one of the most abundant elements within the human body, and there’s no doubt that it contributes significantly to health and wellness (5).

But how does sulfur (and thereby, MSM) contribute to hair growth?

The hair growth cycle consists of three stages (6). They are anagen (growing), telogen (intermediate), and catagen (resting or shedding).

For those looking to promote hair growth and reverse hair loss, anagen is the sought-after stage. MSM is thought to either promote the conversion of telogen to anagen or lengthen anagen, mainly due to the deliverance of sulfur to the middle layer of the hair (7). This both strengthens the strand and encourages further growth.

Additionally, MSM also produces significant amounts of both collagen and keratin (8). These are essential in the development of healthy hair strands.

Read my article about the importance of collagen here.

What Does the Research Say About MSM for Hair Growth?

If you’re considering MSM as a hair growth treatment, you’re in luck – MSM has been shown to have positive effects on hair growth.

A 2009 study aimed to learn whether MSM, when combined with Magnesium Ascorbyl Phosphate (MAP), could be used to effectively treat alopecia in mice (9).

MAP is known to convert hair from telogen phase to anagen phase (10). Researchers, however, wanted to know whether the addition of MSM could bolster these hair-growing effects.

First, researchers prepared the mice by shaving their backs and then applying thioglycolic acid 80% cream to complete hair removal.

Next, researchers prepared a variety of solutions for use in the study.

Some of the solutions contained MAP only, others contained a combination of MAP and MSM, and still others were controls of either saline (negative) or Minoxidil (positive).

MAP and MSM solutions
Source.

Visual scoring of the mice was done as shown below:

visual scoring of the mice
Source.

Now, let’s take a look at the results of the study.

Shown below are visual hair growth scores of six solutions over a number of days.

MAP and MSM hair growth chart results
Source.

As is seen above, the solution of MAP-MSM 10% has the best scores overall, showing increasingly more hair growth as the period of time increased.

And here’s a visual look at the mice.

MAP and MSM visual results
Source.

Is MSM Effective at Treating Hair Loss?

While the study above doesn’t focus solely on MSM, it does provide us with some valuable results.

The study shows that, while MAP alone is effective at promoting hair growth, the solutions containing both MAP and MSM are more effective overall.

The more MSM which was present in the dermal solution, the better the results shown.

Unfortunately, researchers weren’t able to pinpoint the mechanism which makes MSM so effective. However, the results do speak for themselves showing that MSM can be effectively use to treat alopecia in mice.

So, can you use MSM to promote hair growth?

While no human studies have been done, there’s no reason that similar results cannot be seen on humans as they are shown above in the mice.

How to Supplement with MSM

There are two main ways to supplement with MSM.

Eat More MSM-Rich Foods

It’s best to get your nutrients from food sources and, fortunately, there are an abundance of them.

These sources include fruits, vegetables, grains, beer, port wine, coffee, tea, and cow’s milk (11).

Unfortunately, it’s not possible to ingest enough MSM from food sources. That’s where supplements come in.

Use a Supplement

There are a variety of MSM supplements available on the market, though the most common forms include powder, capsule, and tablet.MSM capsules

I recommend you choose the supplementation format you’re most likely to use on a regular basis, as this plays a key role in how well MSM will work for you.

To take MSM, you can add the powder to smoothies or just plain water. As for the capsules and tablets, it’s recommended you take with food if you are sensitive to gastrointestinal side effects which may occur (12).

To lessen the impact of said side effects, begin taking the supplement in doses which are less than recommended.

Gradually work your way up to the recommended dose, pulling back and starting again at a lower dose if side effects are noticed.

Recommended Dosage

As MSM is not currently a drug that is FDA approved for use, there is not yet a universally recommended dosage.

There have been studies which show that MSM is safe to take in larger doses – between 500 milligrams and 3 grams daily (13). But that doesn’t mean you should start with such a high dose.

It’s best to speak with your doctor before you decide on a dosage, or before you even begin with supplementation.

Brands, Availability, and Cost

MSM is available both online and in stores, typically found in the joint support section of the pharmacy. This is due to its sulfurous makeup, which contributes to inflammation and pain relief (14, 15).

Price will vary by brand and location, though Amazon has a few options ranging from 120 capsules at $7.59 to 240 capsules at $16.09.

When choosing a brand, be sure to consider dosage amount.

Conclusion

Further studies are necessary to better understand MSM’s effect on hair growth. However, the current research does give a glimmer of hope to those suffering from hair loss.

Of course, there’s no such thing as the perfect treatment. So while you may want to consider adding an MSM supplement to your routine, you should be sure to take a multi-pronged approach to the problem.

Do you have questions about MSM, or its possibility as a treatment for hair loss? Leave them in the comments section below.

*This article was reviewed by Dr. Anil Simhadri

8 thoughts on “MSM for Hair Growth: Does It Really Work?”

  1. Do you reckon msm and distilled water would be of any use?

    Thinking of adding a high concentration of msm to a spray bottle and trying on my temple

    • Hi Nik,

      The study that was performed on the mice involved a topical solution of MSM. This doesn’t necessarily mean that you’ll see the same results, but I do think it’s worth a try.

      You will want to test on a small area of your skin first, such as the inside of your wrist. You’re unlikely to be allergic to MSM, but it’s better to be safe.

      Regards,

      Steph

  2. Hi Will, I’ve been reading your website for a while since I lived in the UK, now I’m back to my home country (Colombia) and I recently learnt that my grandparents used to use Sulphur soap as a hair treatment, have you heard about this? What do you think about it?

  3. I don’t think that study shows it ‘effectively treat alopecia in mice’. They were shaved on their back.

  4. How about using msm as a leave in conditioner/rinse (for hair growth) which you dont need to wash out? Basically 1 teasppon msm in water pour over scalp then dry hair as normal….

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